英文简介

Psychiatry has suffered tremendously by the limited translational pipeline. Nobel laureate Julius Axelrod's discovery in 1961 of monoamine reuptake by pre-synaptic neurons still forms the basis of contemporary antidepressant treatment. There is a grievous gap between the explosion of knowledge in neuroscience and conceptually novel treatments for our patients. Translational Psychiatry bridges this gap by fostering and highlighting the pathway from discovery to clinical applications, healthcare and global health. We view translation broadly as the full spectrum of work that marks the pathway from discovery to global health, inclusive. The steps of translation that are within the scope of Translational Psychiatry include (i) fundamental discovery, (ii) bench to bedside, (iii) bedside to clinical applications (clinical trials), (iv) translation to policy and health care guidelines, (v) assessment of health policy and usage, and (vi) global health. All areas of medical research, including — but not restricted to — molecular biology, genetics, pharmacology, imaging and epidemiology are welcome as they contribute to enhance the field of translational psychiatry.

中文简介

《转化精神病学》因翻译渠道有限而遭受了巨大的损失。诺贝尔奖获得者朱利叶斯·阿克塞尔罗德于1961年发现突触前神经元对单胺的再摄取，这仍然是当代抗抑郁治疗的基础。神经科学知识的爆炸式增长与我们为患者提供的概念新颖的治疗方法之间存在着巨大的差距。转化精神病学通过培养和强调从发现到临床应用、医疗保健和全球健康的途径来弥合这一差距。我们广泛地将翻译视为标志着从发现到全球健康的全方位工作。翻译精神病学范围内的翻译步骤包括（i）基础发现，（ii）从工作台到床边，（iii）从床边到临床应用（临床试验），（iv）转化为政策和医疗保健指南，（v）评估卫生政策和使用情况，以及（vi）全球卫生。医学研究的所有领域，包括但不限于分子生物学、遗传学、药理学、影像学和流行病学，都是受欢迎的，因为它们有助于加强转化精神病学领域。

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